CRISPR/CAS9 & Mouse Strain, Recourses and Targeted Alleles

Introduction to the Mice Strain and recourses for CRISPER technologies and the gene editing, made easy to follow.

4.70 (21 reviews)
CRISPR/CAS9 & Mouse Strain, Recourses and Targeted Alleles
39 mins
Apr 2021
last update
regular price

What you will learn

Students will learn about the Mice Strains,

Students will get to know the characteristics of different mice strains

Students will see the concepts of the Genetic Drift, and Breeding schemes for the Mice

Students will see the Recourses to be Used in the CRISPR/CAS9

Students will see the Targeted Alleles of the mice when we are using the CRISPR/CAS9

Students will also see Upcoming Future technologies for Gene Editing.


Hi there!

I want to welcome you into this course on the Mouse Strain, Resources, and the Targeted Alleles in the Mice for the Working with CRISPR/CAS9.

This course is more than anything else a pre-CRISPR/CAS9 course where we will be learning about the things one needs to know to get started with this amazing technology.

First of all, we are going to see the Inbred Mouse Strain and why the Inbred mouse is such a good organism to study the humans where we will be learning some of the key features of the Mice strains.

After that, we are going to have a look at the Laboratory Mouse strain and we will also see how this incredible organism has evolved from the wild type of the species.

Then we will move on to the different types of the inbred strain where we will discuss the Standard and the Wild type of the inbred mice strain in detail and also some of their examples.

Afterward, we will see some of the Standard inbred Strain and we will also go into detail about each and every one of these strains where we will be learning about their uses and some characteristics.

Then we are going to see the Genetic drift and the Phenotypic Variations among different strains of the Mice.

Following this, we will go to the Mating Schemes for different strains of the mice and then the Recourses of the mice strains, and we will also see the needs due to which we genetically engineer a mouse,

Then we will go on to the different approaches of genetic engineering, the Forward, and Reverse Genetics.

Then we will give a shot to the Homologous recombination and the Homologous recombination In DNA Repair, and after that, the approach or the Donor Construct.

Finally, we will be moving on to the Targeted Alleles generations in the Mice when we are working with the CRISPR technology, where we will talk about different Selection Methods and then we will move onto different types of Targeted Alleles in mice.

And at the end, we will have a look at some Strengths and Limitations of the mice strain and some Next Generation Technologies also.

I hope you will enjoy the course!

Enroll Now!



Inbred Mouse strain
What are the Learning Outcomes?

Inbred Strain

Mouse as a Modal
Laboratory Mouse Strain
Genetic Drift
What are the Inbred Strains?
Types of the Inbred Mouse Strains
Standard Inbred Mouse Strains
Inbred Breeding Scheme
Phenotype Variations among Laboratory Mouse Strain
Self Check!

Genetic Resources

Mating Schemes
Genetic Resources: Coisogenics
Genetic Resources: Recombinant Inbreds
Genetic Resources: Consomics
Genetic Resources: Congenics

Targeted Alleles Introduction

Human VS Mouse
Why Genetically Engineer a Mouse?
Genetic Engineering
Self Check!

Homologous Recombination

Classic Method Workflow
DNA Repair
Donor Construct
Targeted Allele Generation
Self Check!

Selection Method

Positive and Negative Selection
Self Check!

Targeted Allele Types

Targeted Allele Types
Limitations of Targeted Allele Technology
Next generation Techniques
Self Check!


February 13, 2022
I loved this course, it was very objective and direct. I'm sure it will be very useful in my life as a student and as a professional.
August 12, 2021
This course was very helpful in understanding the CRISPR/Cas9. The material was clearly presented and not overly complicated. A great course for beginners. I'll try to recommend it to others.



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