Biotechnology: Antibodies & their role in Therapeutics

Learn about Antibodies: Their Structure, Types, Functions and Role in Therapeutics & Diagnostics | Immunology | Biology

4.31 (320 reviews)
Udemy
platform
English
language
Science
category
Biotechnology: Antibodies & their role in Therapeutics
1,897
students
5.5 hours
content
May 2023
last update
$84.99
regular price

What you will learn

1. Structure of antibodies

2. Types of light and heavy chains of antibodies

3. Complementarity Determining Regions (CDRs) & how they bind to antigen

4. Immunoglobulin domains

5. Framework region

6. Classes of antibodies: IgG, IgM, IgA, IgE, IgD & their biological activities

7. What is opsonization, ADCC and complement system

8. Pathways of complement activation

9. Regulation of complement system

10. Organization and expression of immunoglobulin genes

11. Mechanism of VJ and VDJ recombination

12. Generation of antibody diversity

13. Somatic Hypermutation

14. Class switching mechanism & factors governing it

15. Expression of membrane bound & secreted form of immunoglobulins

16. B cell receptors (BCRs)

17. Simultaneous expression of IgM and IgD on B cells

18. Regulation of Ig gene transcription

19. Differences between polyclonal and monoclonal antibodies

20. Hybridoma Technology

21. Therapeutic monoclonal antibodies

22. Antibody engineering: Chimeric monoclonal antibodies

23. Humanized monoclonal antibodies

24. Fully human monoclonal antibodies

25. Immunogenicity of engineered monoclonal antibodies

26. Immunotoxins

27. Bispecific antibodies

28. Abzymes

29. Convalescent plasma therapy

30. How is plasma therapy being used for the treatment of COVID-19 disease

Why take this course?

Immune system is the body’s own army that fights against the invading pathogens and toxins. You can compare it to a nation’s defense forces. The army, the air force and the navy all work for the nation's defense. Similarly, the immune system works for the body’s defense. Everywhere around us, there are dangerous bacteria, viruses, parasites and toxins that can attack and harm our body. But our immune system defends us from these pathogens.

Antibodies, also known as immunoglobulins, are one of the crucial warriors produced by our immune system to fight off these nasty invading pathogens. In absence of antibodies, these pathogens can attack our nerve cells, kidney cells, heart cells and other vital parts of the body.

Once attacked by these nasty pathogens, the cells stop functioning, which in turn, may lead to serious illness. But when antibodies come into action, everything changes. They bind to the invading pathogens and prevent them from attacking our body cells.


So what do these antibodies look like, what is their structure and how do they fight off such dangerous pathogens? If you are also curious about these concepts and want to learn the science behind it, then you have come to the right place.

This course is an invaluable resource for medical students, doctors and students of disciplines like biotechnology, biology, immunology, genetics, molecular biology, cell biology and bioinformatics. In the course, the most challenging concepts are presented in a simple and palatable format using animations and graphics.


This course will cover different types of antibodies circulating in the bloodstream & tissue fluids and their respective functions. Additionally this course will also cover the genetic mechanisms which allow our immune system to generate such a diverse pool of antibodies because of which our body is able to recognize and respond to a variety of antigens.

Further in this course, the class switching mechanism, expression of membrane bound & secreted forms of antibodies and regulation of expression of immunoglobulin genes have also been discussed.


Moreover, you will also get to know what is passive immunity and what is active immunity.

We will also discuss the differences between polyclonal and monoclonal antibodies. In this course, the hybridoma technology has been discussed in detail and how it can be used to mass produce monoclonal antibodies? And how monoclonal antibodies can be used as therapeutics?


Additionally this course will introduce you to various engineered therapeutic antibodies like chimeric monoclonal antibodies, humanised monoclonal antibodies and fully human monoclonal antibodies. In this course, you will get to know how the antibody structure can be leveraged to create immunotoxins, bispecific antibodies, abzymes etc for the treatment of cancer, arthritis, other viral, hormonal and autoimmune diseases.


In this course we will discuss what is convalescent plasma therapy or passive antibody therapy and how it is being used for the treatment of COVID-19 disease, the current ongoing pandemic. Last but not the least, the course will also highlight the relevance of antibodies in therapeutics and diagnostics.


With a 30 day return policy, there is nothing to lose. If you feel the course is not worth your money, you can return it and get your money back. Though, we assure you that you will not be disappointed by your wise decision of enrolling in this course.


Who this course is for:

  • The course is designed for medical students, doctors, researchers and students of biology, immunology, biotechnology, genetics, molecular biology, cell biology and bioinformatics disciplines

  • Any student who has immune system as a subject in their curriculum

  • Anyone looking to study biology or immunology at college or university and wants quick, to the point knowledge about antibodies

  • Newly qualified teachers who need some great resources on antibodies

  • Anyone who wants to get an in-depth knowledge about antibodies and our immune system

Screenshots

Biotechnology: Antibodies & their role in Therapeutics - Screenshot_01Biotechnology: Antibodies & their role in Therapeutics - Screenshot_02Biotechnology: Antibodies & their role in Therapeutics - Screenshot_03Biotechnology: Antibodies & their role in Therapeutics - Screenshot_04

Reviews

Alison
August 21, 2023
I find it hard to concentrate on the teacher's voice which does not bring the material to light in an interesting way. The content is good.
adhiraj
April 28, 2023
i have a background with microbiology and this course serves as a great revision along with few new concepts as well...
Prof.
March 23, 2023
Lousy teaching ability. She is very fast reading from her book only, better buy the book then you can self-pace. Illustration is good, though.
Vaibhav
December 23, 2021
the course material is made really easy to understand , and is quite short and made with up to date and relevant material.
Patricia
December 11, 2021
Everyone needs to learn more about the immune system, especially with Covid in the air. I enjoyed the class . BRAVO
Manav
July 8, 2021
This course is definitely complicated and hard to understand for someone who has very basic knowledge of Biology or who is literally a beginner like me. It is suitable for someone in collage or understands more then the basics.
P.Krubaa
April 25, 2021
yes! it is a good match for me. they explain it all very clearly with amazing animations. it is easy to understand. thanks to my lecturer
Arunaa
March 13, 2021
It was a great learning experience , and was more informative which was explained in simple language .
Bruce
December 30, 2020
Yes this is a good match as the company I work for has further innovations when it comes to antibodies. They have a single domain antibody that is so small that it actually goes inside of a cell.
Sakshi
September 4, 2020
Superb course!!!... really it is very efficient, clear explanation in depth with diagrams. Best part of this course is it starts from very basics to a level where we can understand all the concept.
ABHINEET
August 26, 2020
Amazing course!!!All the concepts related to the topic are explained in depth with diagrams and visuals.

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3249112
udemy ID
6/18/2020
course created date
8/23/2020
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