Molecular Biology: Mechanism of Gene Silencing
Learn about mechanisms of gene silencing and their role in plant growth and development

What you will learn
Introduction to gene and protein
What is gene silencing?
Why gene silencing is needed?
Difference between gene silencing and gene therapy
History of gene silencing
Types of gene silencing
What is transcriptional gene silencing (TGS) and post-transcriptional gene silencing (PTGS)
RNA-directed DNA methylation
Genomic imprinting
Paramutation
Transposon silencing
Position effect
RNA interference (RNAi)
Clustered regularly interspaced short palindromic repeats (CRISPR/Cas9)
Nonsense mediated decay (NMD)
Advantages and disadvantages of gene silencing
Applications of gene silencing
Role of gene silencing in plants
Why take this course?
🧬 Course Title: Molecular Biology: Mechanism of Gene Silencing
🚀 Headline: Unlock the Secrets of Gene Silencing in Plant Growth and Development with Expert Dr. Anum Ahmad
🔍 Understanding DNA & Gene Expression Dive into the world of molecular biology where each human cell is a bustling hub of activity, orchestrated by the DNA within its nucleus. Here, the genetic code is transcribed and translated to produce proteins that carry out essential functions for our survival. But what happens when this process needs to be turned off or regulated?
🎯 Exploring Gene Silencing Gene silencing is a critical epigenetic mechanism that fine-tunes the genetic activity within our cells. It's not about turning genes out completely; it's about adjusting their volume knob to ensure health and harmony in the body. This process is pivotal in controlling disease by suppressing harmful genes and can be likened to a skillful conductor fine-tuning an orchestra.
🔑 Two Pathways of Gene Silencing The course will delve into two primary pathways of gene silencing:
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Transcriptional Gene Silencing (TGS): This nuclear process is akin to a guard at the gate, blocking the transcription machinery from accessing certain genes. Techniques like RNA-directed DNA methylation (RdDM), genomic imprinting, paramutation, and transposon silencing are among the methods used to maintain genetic stability.
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Post-transcriptional Gene Silencing (PTGS): This cytoplasmic phenomenon is like a targeted hit on specific mRNA transcripts, ensuring they are degraded before ever fulfilling their protein-coding destiny. Methods such as RNA interference (RNAi) and CRISPR/Cas9 are powerful tools in this process, offering precision and control over gene expression.
🌱 Gene Silencing & Plant Biology The role of gene silencing in plant growth and development is monumental. It's the key to managing transposable elements (TEs), detoxifying natural toxins and allergens, improving quality traits, and providing immunity against stressors like pests and harsh environmental conditions.
👩🏫 Who Should Take This Course? This course is an invaluable resource for:
- Students with a keen interest in biochemistry, molecular biology, biotechnology, and genetics.
- Researchers aiming to advance their understanding of gene regulation and its applications in agriculture and medicine.
- Professionals seeking to stay at the forefront of scientific innovation and discovery in plant biology.
🚀 Join the Learning Journey Embark on an enlightening educational adventure with Dr. Anum Ahmad, a distinguished course instructor in the field of molecular biology. By understanding the mechanisms behind gene silencing, you'll gain insights into nature's intricate designs and contribute to groundbreaking research and technological advancements.
📆 Enroll Now & Explore the Hidden Truths of Nature!